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Should the Current Zero HLA ABDR-Mismatch Priority in Kidney Allocation System Continue?: A Critical Appraisal.

2026-01-13, Kidney360 (10.34067/KID.0000001132) (online)
Douglas S Keith, and Elizabeth Lessmann (?)
In the Kidney Allocation System (KAS), adult kidney candidates who are a zero Human Leukocyte Antigen (HLA) ABDR-mismatch with a potential donor are given priority in the match run over non-zero HLA ABDR-mismatch candidates. Furthermore, KAS allows for the shunting of kidneys to zero-mismatch candidates across compatible ABO blood types, potentially disadvantaging O candidates who have longer waiting times. This study was undertaken to determine who is receiving zero HLA ABDR-mismatch kidneys, the number of donors shunted to non-identical ABO recipients, the impact on dialysis exposure before transplant, and the current patient and graft outcomes.
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